Importing ArrayExpress datasets into R/Bioconductor

نویسندگان

  • Audrey Kauffmann
  • Tim F. Rayner
  • Helen E. Parkinson
  • Misha Kapushesky
  • Margus Lukk
  • Alvis Brazma
  • Wolfgang Huber
چکیده

SUMMARY ArrayExpress is one of the largest public repositories of microarray datasets. R/Bioconductor provides a comprehensive suite of microarray analysis and integrative bioinformatics software. However, easy ways for importing datasets from ArrayExpress into R/Bioconductor have been lacking. Here, we present such a tool that is suitable for both interactive and automated use. AVAILABILITY The ArrayExpress package is available from the Bioconductor project at http://www.bioconductor.org. A users guide and examples are provided with the package.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A pipeline for RNA-seq data processing and quality assessment

SUMMARY We present an R based pipeline, ArrayExpressHTS, for pre-processing, expression estimation and data quality assessment of high-throughput sequencing transcriptional profiling (RNA-seq) datasets. The pipeline starts from raw sequence files and produces standard Bioconductor R objects containing gene or transcript measurements for downstream analysis along with web reports for data qualit...

متن کامل

ArrayExpress update—trends in database growth and links to data analysis tools

The ArrayExpress Archive of Functional Genomics Data (http://www.ebi.ac.uk/arrayexpress) is one of three international functional genomics public data repositories, alongside the Gene Expression Omnibus at NCBI and the DDBJ Omics Archive, supporting peer-reviewed publications. It accepts data generated by sequencing or array-based technologies and currently contains data from almost a million a...

متن کامل

Using the inSilicoMerging package

An increasing amount of gene expression datasets is available through public repositories like for example GEO [2] and ArrayExpress [6]. Combining such data from different studies could be beneficial for the discovery of new biological insights and could increase the statistical power of gene expression analysis. However, the use of different experimentation plans, platforms and methodologies b...

متن کامل

Importing MAGE-ML format microarray data into BioConductor

UNLABELLED The microarray gene expression markup language (MAGE-ML) is a widely used XML (eXtensible Markup Language) standard for describing and exchanging information about microarray experiments. It can describe microarray designs, microarray experiment designs, gene expression data and data analysis results. We describe RMAGEML, a new Bioconductor package that provides a link between cDNA m...

متن کامل

shinyMethyl : interactive quality control of Illumina 450 k

We present shinyMethyl, a Bioconductor package for interactive quality control of DNA methylation data from Illumina 450k arrays. The package summarizes 450k experiments into small exportable R objects from which an interactive interface is launched. Reactive plots allow fast and intuitive quality control assessment of the samples. In addition, exploration of the phenotypic associations is poss...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 25  شماره 

صفحات  -

تاریخ انتشار 2009